DoseLog guides
The GLP-1 guide library.
Deep, plain-language guides on every part of GLP-1 treatment: each medication's side effects, the drugs still in trials, the head-to-head comparisons, and the women's-health questions, all with sources you can check. Not medical advice.
Latest · 54 stories
Every GLP-1 medication compared: the full matrix
Ozempic, Wegovy, Rybelsus, Mounjaro, Zepbound, Saxenda, Victoza, Trulicity, side by side: the active drug, form, what each is approved for, typical weight loss, and the landmark trial behind it.
8 min read
Zepbound vs Mounjaro: the same drug, two labels
Zepbound and Mounjaro are both tirzepatide from Eli Lilly, at the same doses. The difference is what each is approved for and what insurance will cover. Here is how to read it.
7 min read
Retatrutide vs tirzepatide: triple agonist versus the current leader
Retatrutide is an investigational triple agonist with striking phase 2 numbers; tirzepatide (Zepbound, Mounjaro) is the approved dual-agonist leader. What the comparison does and does not tell you.
7 min read
CagriSema vs Zepbound: the amylin combo versus the approved leader
CagriSema is Novo's investigational cagrilintide-plus-semaglutide combination; Zepbound is Lilly's approved tirzepatide. What the trial numbers show, and why availability decides today.
7 min read
Orforglipron vs tirzepatide: the pill versus the injection
Orforglipron is an investigational once-daily GLP-1 pill; tirzepatide (Zepbound, Mounjaro) is the approved injection. What the trade-off between convenience and effect size actually looks like.
7 min read
Zepbound for sleep apnea: what SURMOUNT-OSA actually showed
Zepbound (tirzepatide) is FDA-approved for moderate-to-severe obstructive sleep apnea in adults with obesity. Here is what the SURMOUNT-OSA trial found, and what it means for CPAP.
7 min read
Where to inject a GLP-1: sites, rotation, and why it matters
GLP-1 injections go subcutaneously in the abdomen, thigh, or upper arm, and absorption is equivalent across all three. Why rotation matters and how to stay comfortable.
7 min read
How to inject a GLP-1: a calm, step-by-step walkthrough
A simple, nerve-settling guide to injecting Mounjaro, Zepbound, Wegovy, Ozempic, or Saxenda: preparing the pen, the injection itself, rotating sites, and disposing safely.
6 min read
Ozempic vs Wegovy: the same drug, two labels, one honest answer
Ozempic and Wegovy are both semaglutide from the same maker. The real difference is what each is approved for, the top dose, and what insurance will cover. Here is how to choose.
7 min read
Pemvidutide: the GLP-1/glucagon agonist aimed at fat and liver
Pemvidutide is an investigational GLP-1/glucagon dual agonist targeting obesity and liver disease, with trials suggesting weight loss that spares more muscle.
7 min read
VK2735: Viking's GLP-1/GIP agonist, in both shot and pill
VK2735 is an investigational GLP-1/GIP dual agonist from Viking Therapeutics, in injectable and oral forms. Early trials reported strong weight loss. What's known.
7 min read
Ecnoglutide: the weekly GLP-1 analog advancing in China
Ecnoglutide is an investigational once-weekly GLP-1 analog from Sciwind, with trials in China reporting solid weight loss and glucose control. What's known.
6 min read